{"id":"amoxicillin-hydrate","safety":{"commonSideEffects":[{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Abdominal pain"},{"rate":"1-5%","effect":"Allergic reactions"}]},"_chembl":{"chemblId":"CHEMBL2105950","moleculeType":"Small molecule","molecularWeight":"387.39"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It does this by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, resulting in the disruption of the cell wall synthesis and ultimately leading to bacterial cell death.","oneSentence":"Amoxicillin hydrate is a beta-lactam antibiotic that inhibits cell wall synthesis in bacteria.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:08:56.295Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Uncomplicated urinary tract infections"},{"name":"Acute bacterial otitis media"},{"name":"Pharyngitis and tonsillitis caused by Streptococcus pyogenes"}]},"trialDetails":[{"nctId":"NCT07211880","phase":"NA","title":"Helicobacter Pylori Infection and Gastric Disease in Bhutan: First Community-Wide, Population-Based Study","status":"COMPLETED","sponsor":"Zero Helicobacter IGAN Network","startDate":"2019-12-05","conditions":"H.Pylori, Gastric Cancer, H Pylori Eradication","enrollment":1043},{"nctId":"NCT03219723","phase":"","title":"Drug Use Surveillance of Takecab for \"Supplement to Helicobacter Pylori Eradication\"","status":"COMPLETED","sponsor":"Takeda","startDate":"2015-09-01","conditions":"Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other","enrollment":560},{"nctId":"NCT01934231","phase":"PHASE3","title":"Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2013-08-30","conditions":"Sinusitis, Acute","enrollment":27},{"nctId":"NCT01264822","phase":"","title":"Prognostic Study of Gastric MALT Lymphoma After Eradication of Helicobacter Pylori","status":"COMPLETED","sponsor":"Eisai Co., Ltd.","startDate":"2011-01-13","conditions":"Gastric Low-grade MALT Lymphoma With Helicobacter Pylori Positive","enrollment":108}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":6,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Amoxicillin hydrate","genericName":"Amoxicillin hydrate","companyName":"Takeda","companyId":"takeda","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amoxicillin hydrate is a beta-lactam antibiotic that inhibits cell wall synthesis in bacteria. Used for Uncomplicated urinary tract infections, Acute bacterial otitis media, Pharyngitis and tonsillitis caused by Streptococcus pyogenes.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}