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Amlodipine+standard antihypertensive therapy
Amlodipine+standard antihypertensive therapy is a Calcium channel blocker (dihydropyridine) Small molecule drug developed by Beijing Tiantan Hospital. It is currently FDA-approved for Hypertension (as part of combination antihypertensive therapy). Also known as: Standard antihypertensive therapy.
Amlodipine blocks L-type calcium channels in vascular smooth muscle to reduce blood pressure, used here as part of combination antihypertensive therapy.
Amlodipine blocks L-type calcium channels in vascular smooth muscle to reduce blood pressure, used here as part of combination antihypertensive therapy. Used for Hypertension (as part of combination antihypertensive therapy).
At a glance
| Generic name | Amlodipine+standard antihypertensive therapy |
|---|---|
| Also known as | Standard antihypertensive therapy |
| Sponsor | Beijing Tiantan Hospital |
| Drug class | Calcium channel blocker (dihydropyridine) |
| Target | L-type voltage-gated calcium channel |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle cells and cardiac muscle, leading to vasodilation and reduced peripheral vascular resistance. When combined with standard antihypertensive agents, it provides additive blood pressure reduction through complementary mechanisms. This combination approach is used to achieve target blood pressure control in patients with hypertension.
Approved indications
- Hypertension (as part of combination antihypertensive therapy)
Common side effects
- Peripheral edema
- Headache
- Flushing
- Fatigue
- Dizziness
Key clinical trials
- Short-Term Effects of Antihypertensive Drugs on Postural Balance and Fall Risk (NA)
- OBPM_Meds2023: Multicentric Prospective Clinical Study to Evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) Device Compared to Standard Home Blood Pressure Monitoring (HBPM) in Hypertensive Patients When Blood Pressure Lowering Medications Intake (NA)
- Rapid Management of Resistant Hypertension in the Public Health System (Fast Control) (NA)
- Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2) (PHASE2)
- Hypertension, Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial) (PHASE2)
- Arterial Stiffness and Blood Pressure (NA)
- Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes (PHASE4)
- Standardized Antihypertensive Treatment Protocol (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Amlodipine+standard antihypertensive therapy CI brief — competitive landscape report
- Amlodipine+standard antihypertensive therapy updates RSS · CI watch RSS
- Beijing Tiantan Hospital portfolio CI
Frequently asked questions about Amlodipine+standard antihypertensive therapy
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Related
- Drug class: All Calcium channel blocker (dihydropyridine) drugs
- Target: All drugs targeting L-type voltage-gated calcium channel
- Manufacturer: Beijing Tiantan Hospital — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Hypertension (as part of combination antihypertensive therapy)
- Also known as: Standard antihypertensive therapy
- Compare: Amlodipine+standard antihypertensive therapy vs similar drugs
- Pricing: Amlodipine+standard antihypertensive therapy cost, discount & access