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Aroft (AFLOQUALONE)

Phase 2 active Small molecule

Aroft (generic name: AFLOQUALONE) is a drug. It is currently in Phase 2 development.

Aroft works by binding to a specific target, although its exact mechanism of action is currently unknown.

Aroft (AFLOQUALONE) is a small molecule modality with unknown target and drug class. Its commercial status is unclear, and it has not been approved by the FDA for any indications. As a result, there is limited information available on its pharmacokinetic properties, such as half-life and bioavailability. Aroft's safety profile and potential side effects are also unknown. Further research is needed to determine its efficacy and potential therapeutic applications.

Likelihood of approval
15.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameAFLOQUALONE
ModalitySmall molecule
Therapeutic areaOther
PhasePhase 2

Mechanism of action

Think of Aroft like a key that fits into a lock. The lock is a specific target in the body, and when the key (Aroft) binds to it, it can help to turn off or turn on certain processes that are involved in the development of a disease. However, since the target and mechanism of action are unknown, it's like trying to find the right key without knowing what the lock looks like.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Aroft

What is Aroft?

Aroft (AFLOQUALONE) is a Small molecule drug.

How does Aroft work?

Aroft works by binding to a specific target, although its exact mechanism of action is currently unknown.

What is the generic name of Aroft?

AFLOQUALONE is the generic (nonproprietary) name of Aroft.

What development phase is Aroft in?

Aroft is in Phase 2.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing