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Adrenaline nasal pack
Adrenaline nasal pack is a Sympathomimetic Small molecule drug developed by Shaheed Mohtarma Benazir Bhutto Institue of Trauma. It is currently in Phase 2 development for Anaphylaxis treatment.
Adrenaline nasal pack works by releasing adrenaline into the nasal passages to rapidly increase blood pressure and improve breathing in cases of anaphylaxis or severe allergic reactions.
Adrenaline nasal packs are used in nasal surgeries, such as septoplasty, to prevent postoperative agitation. The mechanism of adrenaline nasal packs is through the action of adrenaline as a small molecule, although the specific details of its mechanism are not provided in the available information.
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Baseline phase 2 → approval rate
+15.3pp
Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
| Regulator | Country | Likely year | Lag vs FDA |
|---|---|---|---|
| FDA | US | 2031–2034 | — |
| EMA | EU | 2032–2035 | +0.7 yr |
| MHRA | GB | 2032–2035 | +0.7 yr |
| Health Canada | CA | 2032–2036 | +0.9 yr |
| TGA | AU | 2032–2036 | +1.2 yr |
| PMDA | JP | 2032–2036 | +1.5 yr |
| NMPA | CN | 2033–2037 | +2.3 yr |
| MFDS | KR | 2032–2036 | +1.4 yr |
| CDSCO | IN | 2032–2037 | +1.8 yr |
| ANVISA | BR | 2033–2037 | +2.3 yr |
Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).
Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.
At a glance
| Generic name | Adrenaline nasal pack |
|---|---|
| Sponsor | Shaheed Mohtarma Benazir Bhutto Institue of Trauma |
| Drug class | Sympathomimetic |
| Target | Adrenaline receptor |
| Modality | Small molecule |
| Therapeutic area | Emergency Medicine |
| Phase | Phase 2 |
Mechanism of action
Adrenaline, also known as epinephrine, is a potent stimulant that increases heart rate, blood pressure, and breathing rate. When administered via a nasal pack, it quickly reaches the bloodstream and helps to counteract the life-threatening symptoms of anaphylaxis, such as difficulty breathing and rapid heartbeat.
Approved indications
- Anaphylaxis treatment
Common side effects
- Nausea
- Headache
- Palpitations
- Tremors
- Dizziness
Key clinical trials
- Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block (NA)
- Different Techniques for Prevention of Complications After Septoplasty Operation (NA)
- Accuracy of Computer Guided Screw Holes Locating Guide and Patient Specific Champy Plate vs Conventional Champy Plate Osteosynthesis in Management of Mandibular Angle Fracture: Randomized Controlled Trial (NA)
- Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation (PHASE2, PHASE3)
- Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy (NA)
- The Role of the Submucosal Conchoplasty Technique in Improving the Postoperative Middle Meatus Outcome After ESS (NA)
- Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation (NA)
- Endoscopic-guided Versus Cotton-tipped Applicator Gauze Pledgetting for Nasal Anesthesia Before Transnasal Endoscopy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Adrenaline nasal pack CI brief — competitive landscape report
- Adrenaline nasal pack updates RSS · CI watch RSS
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma portfolio CI
Frequently asked questions about Adrenaline nasal pack
What is Adrenaline nasal pack?
How does Adrenaline nasal pack work?
What is Adrenaline nasal pack used for?
Who makes Adrenaline nasal pack?
What drug class is Adrenaline nasal pack in?
What development phase is Adrenaline nasal pack in?
What are the side effects of Adrenaline nasal pack?
What does Adrenaline nasal pack target?
Related
- Drug class: All Sympathomimetic drugs
- Target: All drugs targeting Adrenaline receptor
- Manufacturer: Shaheed Mohtarma Benazir Bhutto Institue of Trauma — full pipeline
- Therapeutic area: All drugs in Emergency Medicine
- Indication: Drugs for Anaphylaxis treatment
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing