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Administration of etoricoxib
Administration of etoricoxib is a Selective COX-2 inhibitor (coxib) Small molecule drug developed by University of Regensburg. It is currently in Phase 3 development for Rheumatoid arthritis, Osteoarthritis, Acute pain.
Etoricoxib selectively inhibits cyclooxygenase-2 (COX-2) to reduce prostaglandin production and inflammation.
Etoricoxib selectively inhibits cyclooxygenase-2 (COX-2) to reduce prostaglandin production and inflammation. Used for Rheumatoid arthritis, Osteoarthritis, Acute pain.
At a glance
| Generic name | Administration of etoricoxib |
|---|---|
| Sponsor | University of Regensburg |
| Drug class | Selective COX-2 inhibitor (coxib) |
| Target | COX-2 (Cyclooxygenase-2) |
| Modality | Small molecule |
| Therapeutic area | Rheumatology / Pain Management |
| Phase | Phase 3 |
Mechanism of action
Etoricoxib is a selective COX-2 inhibitor that preferentially blocks the COX-2 enzyme over COX-1, thereby reducing the synthesis of pro-inflammatory prostaglandins while theoretically sparing the protective prostaglandins produced by COX-1 in the gastrointestinal tract and kidneys. This selective inhibition provides anti-inflammatory, analgesic, and antipyretic effects with a potentially improved gastrointestinal safety profile compared to non-selective NSAIDs.
Approved indications
- Rheumatoid arthritis
- Osteoarthritis
- Acute pain
- Ankylosing spondylitis
Common side effects
- Hypertension
- Edema
- Dyspepsia
- Headache
- Cardiovascular events
Key clinical trials
- Comparative Bioavailability Study Between Etoricoxib / Betamethasone Administered Individually or in Combination (PHASE1)
- Assessing the Benefits of Dry Needling for Low Back Pain When Combined With Regular Treatment (PHASE4)
- Etoricoxib in Patients With Parkinsonian Disease (PHASE2)
- Efficacy and Safety of Etoricoxib/Tizanidine Versus Etoricoxib for Acute Low Back Pain Associated to Muscle Spasm (PHASE3)
- Efficacy and Safety of Etoricoxib/Betamethasone Combination in Acute Bursitis, Tendinitis and Synovitis (PHASE3)
- Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)
- Venous Cannulation Pain to Guide Choice of Anesthetic Method (NA)
- Efficacy Anda Safety of Etoricoxib With Betamethasone for the Treatment of Acute Gout Arthritis (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Administration of etoricoxib CI brief — competitive landscape report
- Administration of etoricoxib updates RSS · CI watch RSS
- University of Regensburg portfolio CI
Frequently asked questions about Administration of etoricoxib
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Related
- Drug class: All Selective COX-2 inhibitor (coxib) drugs
- Target: All drugs targeting COX-2 (Cyclooxygenase-2)
- Manufacturer: University of Regensburg — full pipeline
- Therapeutic area: All drugs in Rheumatology / Pain Management
- Indication: Drugs for Rheumatoid arthritis
- Indication: Drugs for Osteoarthritis
- Indication: Drugs for Acute pain
- Compare: Administration of etoricoxib vs similar drugs
- Pricing: Administration of etoricoxib cost, discount & access