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Active comparator: Synovian Inj.
Synovian is a hyaluronic acid-based intra-articular injection that lubricates and cushions the joint to reduce pain and improve mobility in osteoarthritis.
Synovian is a hyaluronic acid-based intra-articular injection that lubricates and cushions the joint to reduce pain and improve mobility in osteoarthritis. Used for Osteoarthritis of the knee.
At a glance
| Generic name | Active comparator: Synovian Inj. |
|---|---|
| Also known as | Synovian Inj. |
| Sponsor | Yooyoung Pharmaceutical Co., Ltd. |
| Drug class | Viscosupplement (hyaluronic acid) |
| Target | Synovial fluid replacement; hyaluronic acid |
| Modality | Small molecule |
| Therapeutic area | Orthopedics / Rheumatology |
| Phase | Phase 3 |
Mechanism of action
Synovian works by supplementing the synovial fluid in the joint space, restoring viscoelastic properties that are depleted in osteoarthritis. The hyaluronic acid provides lubrication and shock absorption, reducing friction between cartilage surfaces and alleviating pain during movement. This viscosupplementation approach aims to improve joint function and delay cartilage degradation.
Approved indications
- Osteoarthritis of the knee
Common side effects
- Injection site pain or swelling
- Transient joint effusion
- Local inflammatory reaction
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |