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Acofide (ACOTIAMIDE)
Acofide (generic name: ACOTIAMIDE) is a Small molecule drug developed by Zeria. It is currently FDA-approved for Nonulcer dyspepsia.
ACOTIAMIDE (Acofide), marketed by Zeria, is a nonulcer dyspepsia treatment that inhibits acetylcholinesterase, positioning it in a competitive market alongside metoclopramide and cisapride. Acofide's key strength lies in its distinct mechanism of action, which differentiates it from same-class competitors like metoclopramide and cisapride. The primary risk to Acofide is the key composition patent expiry in 2028, which could lead to increased competition from generics.
At a glance
| Generic name | ACOTIAMIDE |
|---|---|
| Sponsor | Zeria |
| Target | Acetylcholinesterase |
| Modality | Small molecule |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
Approved indications
- Nonulcer dyspepsia
Common side effects
Key clinical trials
- A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia (PHASE3)
- Comparing Acotiamide and Itopride for the Management of Indigestion (PHASE4)
- Acotiamide vs Itopride in Postprandial Distress Syndrome (PHASE3)
- Helicobacter Pylori Eradication in Functional Dyspepsia (NA)
- Effect of Acotiamide on Gastric Motility and Satiation in Healthy Volunteers (NA)
- YM443 in Subjects With Functional Dyspepsia (PHASE2)
- Phase III, Long-term, Open-label Safety Study of Z-338 (PHASE3)
- To Evaluate the Efficacy and Safety in Subjects With Functional Dyspepsia (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Acofide CI brief — competitive landscape report
- Acofide updates RSS · CI watch RSS
- Zeria portfolio CI
Frequently asked questions about Acofide
What is Acofide?
What is Acofide used for?
Who makes Acofide?
What is the generic name of Acofide?
What development phase is Acofide in?
What does Acofide target?
Related
- Target: All drugs targeting Acetylcholinesterase
- Manufacturer: Zeria — full pipeline
- Therapeutic area: All drugs in Neuroscience
- Indication: Drugs for Nonulcer dyspepsia
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing