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Acnatac® Gel right face

GWT-TUD GmbH · FDA-approved active Small molecule

Acnatac® Gel combines clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial and keratolytic agent) to reduce acne-causing bacteria and promote skin cell turnover.

Acnatac® Gel combines clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial and keratolytic agent) to reduce acne-causing bacteria and promote skin cell turnover. Used for Acne vulgaris.

At a glance

Generic nameAcnatac® Gel right face
Also known asClindamycin 1%, Tretinoin 0,025%
SponsorGWT-TUD GmbH
Drug classTopical antibiotic combination
TargetBacterial ribosome (clindamycin); reactive oxygen species generation (benzoyl peroxide)
ModalitySmall molecule
Therapeutic areaDermatology
PhaseFDA-approved

Mechanism of action

Clindamycin inhibits bacterial protein synthesis, reducing Cutibacterium acnes (formerly Propionibacterium acnes) proliferation. Benzoyl peroxide generates reactive oxygen species that kill bacteria and help unclog pores by promoting desquamation. The combination addresses both bacterial and comedonal components of acne.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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