{"id":"acnatac-gel-right-face","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation/erythema"},{"rate":null,"effect":"Dryness"},{"rate":null,"effect":"Peeling"},{"rate":null,"effect":"Contact dermatitis"}]},"_chembl":{"chemblId":"CHEMBL2109015","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Clindamycin inhibits bacterial protein synthesis, reducing Cutibacterium acnes (formerly Propionibacterium acnes) proliferation. Benzoyl peroxide generates reactive oxygen species that kill bacteria and help unclog pores by promoting desquamation. The combination addresses both bacterial and comedonal components of acne.","oneSentence":"Acnatac® Gel combines clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial and keratolytic agent) to reduce acne-causing bacteria and promote skin cell turnover.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:17:12.825Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acne vulgaris"}]},"trialDetails":[{"nctId":"NCT02731105","phase":"PHASE4","title":"Pilot Study of Tolerability and Effectivity of Two Combination Topical Acne Products","status":"COMPLETED","sponsor":"GWT-TUD GmbH","startDate":"2015-02","conditions":"Acne Vulgaris","enrollment":22}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Clindamycin 1%, Tretinoin 0,025%"],"phase":"marketed","status":"active","brandName":"Acnatac® Gel right face","genericName":"Acnatac® Gel right face","companyName":"GWT-TUD GmbH","companyId":"gwt-tud-gmbh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Acnatac® Gel combines clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial and keratolytic agent) to reduce acne-causing bacteria and promote skin cell turnover. Used for Acne vulgaris.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}