Last reviewed 2026-05-19 · How we verify

Glycyrrhetinyl Acetate (acetoxolone)

unknown active ✓ Verified May 2026

Glycyrrhetinyl Acetate (generic name: acetoxolone) is a acetoxolone drug. It is currently in unknown development for Gastritis.

Acetoxolone works by inhibiting the enzyme that converts cortisol into its inactive form, allowing more cortisol to be available to reduce inflammation.

Glycyrrhetinyl Acetate is an acetyl derivative of glycyrrhetinic acid. It is found in Echinopora lamellosa and is related to Acetoxolone, which is used to treat peptic ulcer and gastroesophageal reflux disease.

At a glance

Generic name	acetoxolone
Drug class	acetoxolone
Target	Corticosteroid 11-beta-dehydrogenase isozyme 2
Therapeutic area	Gastroenterology
Phase	unknown

Mechanism of action

Think of cortisol like a fire extinguisher. Normally, the body converts cortisol into an inactive form, but acetoxolone blocks this process, allowing more cortisol to be available to put out the fire of inflammation in the stomach.

Approved indications

Gastritis

Common side effects

No common side effects on file.

Competitive intelligence

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Frequently asked questions about Glycyrrhetinyl Acetate

What is Glycyrrhetinyl Acetate?

Glycyrrhetinyl Acetate (acetoxolone) is a acetoxolone drug, indicated for Gastritis.

How does Glycyrrhetinyl Acetate work?

Acetoxolone works by inhibiting the enzyme that converts cortisol into its inactive form, allowing more cortisol to be available to reduce inflammation.

What is Glycyrrhetinyl Acetate used for?

Glycyrrhetinyl Acetate is indicated for Gastritis.

What is the generic name of Glycyrrhetinyl Acetate?

acetoxolone is the generic (nonproprietary) name of Glycyrrhetinyl Acetate.

What drug class is Glycyrrhetinyl Acetate in?

Glycyrrhetinyl Acetate belongs to the acetoxolone class. See all acetoxolone drugs at /class/acetoxolone.

What development phase is Glycyrrhetinyl Acetate in?

Glycyrrhetinyl Acetate is in unknown.

What does Glycyrrhetinyl Acetate target?

Glycyrrhetinyl Acetate targets Corticosteroid 11-beta-dehydrogenase isozyme 2 and is a acetoxolone.

Drug class: All acetoxolone drugs
Target: All drugs targeting Corticosteroid 11-beta-dehydrogenase isozyme 2
Manufacturer: — full pipeline
Therapeutic area: All drugs in Gastroenterology
Indication: Drugs for Gastritis

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing