Last reviewed · How we verify
Zollinger-Ellison syndrome
Approved treatments
- Dexpure
Dexpure works by irreversibly inhibiting the H+/K+ ATPase enzyme in the stomach lining, reducing acid production. - Zantac · GSK (originally Glaxo)
- Pepcid · Generic (originally Yamanouchi/Merck)
Competitively blocks histamine H2 receptors on gastric parietal cells, reducing basal and stimulated acid secretion. - Prevacid · Vanderbilt University Medical Center
- Nexium · AstraZeneca
- Protonix · Generic (originally Byk Gulden/Altana/Nycomed)
Irreversibly inhibits the gastric proton pump (H+/K+ ATPase), suppressing stomach acid secretion. - Pantoprazole Sodium · Pfizer
Pantoprazole suppresses gastric acid by covalently binding the (H+, K+)-ATPase enzyme at parietal cells. - Prilosec · AstraZeneca (originally Astra AB)
Irreversibly inhibits the hydrogen-potassium ATPase (proton pump) in gastric parietal cells, potently suppressing stomach acid secretion. - Aciphex · University of Utah
- Rabeprazole 40 mg · Pfizer
- Tagamet
- Aciphex · Waylis
Aciphex works by irreversibly inhibiting the potassium-transporting ATPase enzyme in the stomach lining, reducing acid production. - Rabeprazol · Janssen-Cilag, S.A.
- Omeprazol · RenJi Hospital
- Pantoprazol · Northern Orthopaedic Division, Denmark
- Prevacid · Generic (originally Takeda)
Irreversibly inhibits the gastric proton pump to suppress acid secretion.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Zollinger-Ellison syndrome patent landscape — cliff calendar, originator estates, attackable patents
- Zollinger-Ellison syndrome treatment landscape brief
- Zollinger-Ellison syndrome treatment updates RSS
Frequently asked questions about Zollinger-Ellison syndrome
What drugs treat Zollinger-Ellison syndrome?
Tracked treatments include Dexpure, Zantac, Pepcid, Prevacid, Nexium, Protonix, Pantoprazole Sodium, Prilosec.
What is the treatment for Zollinger-Ellison syndrome?
Standard treatment for Zollinger-Ellison syndrome includes Dexpure, Zantac, Pepcid, Prevacid, Nexium. See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Zollinger-Ellison syndrome patent cliff · Zollinger-Ellison syndrome CI report
- Treatment: Dexpure
- Treatment: Zantac · GSK (originally Glaxo)
- Treatment: Pepcid · Generic (originally Yamanouchi/Merck)
- Treatment: Prevacid · Vanderbilt University Medical Center
- Treatment: Nexium · AstraZeneca
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing