Hormone Refractory Prostate Cancer — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for hormone refractory prostate cancer. 34 active patents protecting 2 drugs from 2+ originators. First major cliff: 2030. Daily refresh.

2
Approved drugs
34
Active US patents
40/100
Avg vulnerability
$4.2B
Annual revenue covered

Originators in Hormone Refractory Prostate Cancer

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

AstraZeneca 25 patents Bayer 9 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating hormone refractory prostate cancer. Each bar = one year. Y-axis scaled to peak year (12 patents).

7
27
1
28
12
29
3
30
3
31
1
33
3
36
1
38

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Lynparza
olaparib
 AstraZeneca 25 59 $2.6B 2027-08-12
Nubeqa
darolutamide
 Bayer 9 20 $1.6B 2030-10-27

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8143241 Lynparza method of use 75 2027-08-12
8071579 Lynparza method of use 75 2027-08-12
8143241 Lynparza method of use 75 2027-08-12
8143241 Lynparza method of use 75 2027-08-12
8071579 Lynparza method of use 75 2027-08-12
11970530 Lynparza method of use 75 2041-10-25
11970530 Lynparza method of use 75 2041-10-25
8859562 Lynparza method of use 68 2031-08-04
8859562 Lynparza method of use 68 2031-08-04
8859562 Lynparza method of use 68 2031-08-04

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
11168058 Nubeqa composition of matter 0 2038-02-27
10010530 Nubeqa composition of matter 0 2036-01-28
10383853 Nubeqa composition of matter 0 2036-01-28
10711013 Nubeqa composition of matter 0 2030-10-27
11046713 Nubeqa composition of matter 0 2030-10-27
8247416 Lynparza composition of matter 17 2028-09-24
7449464 Lynparza composition of matter 17 2027-09-08
7449464 Lynparza composition of matter 17 2027-09-08
12329742 Nubeqa formulation 38 2042-06-17
10835515 Nubeqa method of use 45 2036-01-28

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