Chronic Lymphoid Leukemia Disease — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for chronic lymphoid leukemia disease. 509 active patents protecting 5 drugs from 4+ originators. First major cliff: 2029. Daily refresh.

5
Approved drugs
509
Active US patents
52/100
Avg vulnerability
$6.8B
Annual revenue covered

Originators in Chronic Lymphoid Leukemia Disease

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

AbbVie 478 patents Baxter 15 patents Secura 12 patents Generic (originally Schering) 4 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating chronic lymphoid leukemia disease. Each bar = one year. Y-axis scaled to peak year (123 patents).

70
26
90
27
8
28
2
29
3
30
123
31
14
32
96
33
30
34
30
35
42
36
1
39

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Imbruvica
ibrutinib
 AbbVie 448 43 $3.2B 2026-12-28
Venclexta
venetoclax
 AbbVie 30 47 $2.6B 2030-05-26
Cytoxan (Lyophilized)
cyclophosphamide
 Baxter 15 49 $1.0B 2035-06-26
Copiktra
DUVELISIB
 Secura 12 47 — 2029-01-05
Deltasone
prednisone
 Generic (originally Schering) 4 76 — 2027-08-03

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8168218 Deltasone method of use 80 2028-01-07
8703780 Imbruvica method of use 76 2026-12-28
8952015 Imbruvica method of use 76 2026-12-28
8476284 Imbruvica method of use 76 2026-12-28
8563563 Imbruvica method of use 76 2027-04-26
9504699 Deltasone method of use 75 2027-08-03
9504699 Deltasone method of use 75 2027-08-03
9504699 Deltasone method of use 75 2027-08-03
9216982 Copiktra method of use 75 2029-01-05
9216982 Copiktra method of use 75 2029-01-05

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
10125140 Imbruvica composition of matter 0 2033-06-03
10106548 Imbruvica composition of matter 0 2033-06-03
10106548 Imbruvica composition of matter 0 2033-06-03

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