Amyloidosis — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for amyloidosis. 13 active patents protecting 3 drugs from 2+ originators. First major cliff: 2031. Daily refresh.

3
Approved drugs
13
Active US patents
57/100
Avg vulnerability
$1.4B
Annual revenue covered

Originators in Amyloidosis

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Bristol-Myers Squibb 8 patents Foldrx Pharms 5 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating amyloidosis. Each bar = one year. Y-axis scaled to peak year (7 patents).

4
26
1
31
7
32
1
35

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Acetadote
Acetylcysteine
 Bristol-Myers Squibb 8 64 — 2031-07-21
Vyndaqel
tafamidis
 Foldrx Pharms 3 55 $1.4B 2026-12-19
Vyndaqel
Tafamidis Meglumine
 Foldrx Pharms 2 51 — 2026-12-19

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
7214696 Vyndaqel method of use 80 2026-12-19
7214696 Vyndaqel method of use 80 2026-12-19
8722738 Acetadote method of use 73 2032-04-06
9327028 Acetadote method of use 68 2031-07-21
8747894 Acetadote method of use 68 2032-05-08
9561204 Acetadote method of use 68 2032-05-08
8747894 Acetadote method of use 68 2032-05-08
9561204 Acetadote method of use 68 2032-05-08
9770441 Vyndaqel method of use 62 2035-08-31
9427421 Acetadote formulation 48 2032-05-08

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
7214695 Vyndaqel composition of matter 22 2026-12-19
7214695 Vyndaqel composition of matter 22 2026-12-19
9427421 Acetadote formulation 48 2032-05-08
9427421 Acetadote formulation 48 2032-05-08
9770441 Vyndaqel method of use 62 2035-08-31
9561204 Acetadote method of use 68 2032-05-08
8747894 Acetadote method of use 68 2032-05-08
9561204 Acetadote method of use 68 2032-05-08
8747894 Acetadote method of use 68 2032-05-08
9327028 Acetadote method of use 68 2031-07-21

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