Last reviewed · How we verify
Allergic Rhinitis Prevention
Approved treatments
- Verdeso · Padagis Us
- Pulmicort Respules · AstraZeneca K.K.
- Nasonex · University of Alberta
- Rodinolone
- Aerospan Hfa
- Elocon · Merck & Co.
Elocon works by binding to the progesterone receptor, which reduces inflammation and immune response in the body. - MOMETASONE
12.1 Mechanism of Action Mometasone furoate nasal spray is a corticosteroid demonstrating potent anti-inflammatory properties. The precise mechanism of corticosteroid action on allergic rhinitis is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. In two clinical studies utilizing nasal antigen challenge, mometasone furoate nasal spray decreased some markers of the early- and late-phase allergic response. These observations included decreases (vs. placebo) in histamine and eosinophil cationic protein levels, and reductions (vs. baseline) in eosinophils, neutrophils, and epithelial cell adhesion proteins. The clinical significance of these findings is not known. The effect of mometasone furoate nasal spray on nasal mucosa following 12 months of treatment was examined in 46 patients with allergic rhinitis. There was no evidence of atrophy and there was a marked reduction in intraepithelial eosinophilia and inflammatory cell infiltration (e.g., eosinophils, lymphocytes, monocytes, neutrophils, and plasma cells).
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Allergic Rhinitis Prevention patent landscape — cliff calendar, originator estates, attackable patents
- Allergic Rhinitis Prevention treatment landscape brief
- Allergic Rhinitis Prevention treatment updates RSS
Frequently asked questions about Allergic Rhinitis Prevention
What drugs treat Allergic Rhinitis Prevention?
Tracked treatments include Verdeso, Pulmicort Respules, Nasonex, Rodinolone, Aerospan Hfa, Elocon, MOMETASONE.
What is the treatment for Allergic Rhinitis Prevention?
Standard treatment for Allergic Rhinitis Prevention includes Verdeso, Pulmicort Respules, Nasonex, Rodinolone, Aerospan Hfa. See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Allergic Rhinitis Prevention patent cliff · Allergic Rhinitis Prevention CI report
- Treatment: Verdeso · Padagis Us
- Treatment: Pulmicort Respules · AstraZeneca K.K.
- Treatment: Nasonex · University of Alberta
- Treatment: Rodinolone
- Treatment: Aerospan Hfa
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing