Stiefel, a GSK Company

Quick facts

Marketed products

• 0.25 % Miconazole Nitrate Ointment
• Acitretin (also called U0279) · Dermatology
  Acitretin is a retinoid that binds to retinoid receptors in the nucleus, modulating gene expression to reduce keratinocyte proliferation and promote differentiation.
• BENZOYL PEROXIDE/ ADAPALENE · Dermatology
  Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover, while adapalene normalizes skin cell differentiation and reduces inflammation.
• BENZOYL PEROXIDE/ CLINDAMYCIN · Dermatology
  Benzoyl peroxide kills acne-causing bacteria and reduces sebum production, while clindamycin is an antibiotic that inhibits bacterial protein synthesis.
• Benzoyl peroxide with clindamycin · Dermatology
  Benzoyl peroxide kills acne-causing bacteria and reduces sebum production, while clindamycin is an antibiotic that inhibits bacterial protein synthesis.
• Benzoyl peroxide with clindamycin and doxycycline
• Clindamycin and BPO 5% gel · Dermatology
  Clindamycin kills acne-causing bacteria while benzoyl peroxide oxidizes and destroys bacterial cell membranes and reduces sebum production.
• Clindamycin Gel (clindamycin ) · Dermatology
  Clindamycin is a lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
• Clobetasol propionate foam · Dermatology
  Clobetasol propionate is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin by binding to glucocorticoid receptors.
• Clobex lotion · Dermatology
  Clobetasol propionate is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin by binding to glucocorticoid receptors.
• Duac Gel · Dermatology
  Duac Gel combines benzoyl peroxide and clindamycin to kill acne-causing bacteria and reduce inflammation in acne lesions.
• Duac® Gel / Differin® Gel · Dermatology
  Duac® Gel combines clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial oxidizing agent) to reduce acne-causing bacteria and inflammation, while Differin® Gel contains adapalene (a retinoid) that normalizes skin cell turnover and reduces comedone formation.
• Epiduo Gel
• Olux-E Foam
• Tretinoin Gel (tretinoin) · Dermatology
  Tretinoin is a vitamin A derivative that binds to retinoic acid receptors in skin cells to promote cell turnover, reduce sebum production, and normalize keratinization.

Phase 3 pipeline

• Calcipotriene Foam · Dermatology
  Calcipotriene is a vitamin D3 analog that binds to vitamin D receptors on skin cells to regulate cell proliferation and differentiation, reducing excessive skin cell growth characteristic of psoriasis.
• CT Gel · Dermatology
  CT Gel is a topical antimicrobial gel formulation designed to reduce bacterial colonization and biofilm formation on skin surfaces.
• CTGel/ BPO Wash · Dermatology
  CTGel/BPO Wash is a topical formulation combining clindamycin and benzoyl peroxide to reduce acne-causing bacteria and inflammation on the skin.
• Retpamulin Ointment, 1% · Infectious Disease / Dermatology
  Retpamulin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation and bacterial growth.
• Soap Free Cleanser and CTGel · Dermatology
  Soap Free Cleanser and CTGel works by physically removing dirt and bacteria from the skin.
• Tazarotene Foam · Dermatology
  Tazarotene Foam is a topical retinoid that modulates cell growth and differentiation.
• U0267 · Oncology
  U0267 is a small molecule drug that targets the molecular target.
• U0267 Foam · Dermatology
  U0267 Foam is a topical corticosteroid formulation designed to reduce inflammation and provide therapeutic benefit when applied directly to affected skin areas.

Phase 2 pipeline

• Tazarotene cream

Phase 1 pipeline

• Albaconozole · Other
• Differin™, 0.1% adapalene gel
• Sodium Laural Sulfate
• Tazaroc Gel
• Tazarotene Foam without irradiation
• W0027

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• Stiefel, a GSK Company portfolio CI brief
• Stiefel, a GSK Company pipeline updates RSS