Bausch Health Companies Inc. (BHC)

Quick facts

Marketed products

• Xifaxan · Gastroenterology · revenue 1500
• Bepreve · Other
  Bepotastine blocks H1 receptors and inhibits histamine release from mast cells.
• Besivance · Infectious Disease
  Besivance works by inhibiting bacterial DNA replication.
• Targretin · Oncology
  Targretin works by binding to the retinoic acid receptor RXR-beta, which helps regulate cell growth and differentiation.
• Xibrom · Ophthalmology
  Xibrom works by blocking the production of prostaglandins, which are hormone-like substances that cause pain and inflammation.
• Chlordiazepoxide Hydrochloride · Neuroscience
• Loprox · Metabolic
• Migranal · Neuroscience
• Jublia · Infectious Disease
  Jublia works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is essential for the production of ergosterol, a critical component of fungal cell membranes.
• Edecrin · Immunology
• Ancobon · Metabolic
• Locoid · Immunology
  Locoid works by binding to the glucocorticoid receptor, triggering a response that reduces inflammation and immune responses.
• Aldara · Oncology
  Aldara works by activating the immune system to recognize and attack abnormal cells.
• Vyzulta · Cardiovascular
  Vyzulta works by activating the Prostaglandin F2-alpha receptor, which increases the outflow of aqueous humor from the eye, thereby reducing intraocular pressure.
• Levo-Dromoran · Neuroscience
  Levorphanol binds primarily to mu-opioid receptors to produce analgesia, with no ceiling effect for pain relief.
• Xiidra · Immunology
  Xiidra works by blocking the interaction between immune cells and the surface of the eye, reducing inflammation and promoting tear production.
• Loteprednol Etabonate · Immunology
• Lotemax · Immunology
• Luzu · Infectious Disease
  Luzu works by inhibiting the growth of fungi by targeting a specific enzyme.
• Oxsoralen-Ultra · Oncology
  Oxsoralen-Ultra works by generating free radicals when exposed to ultraviolet A (UVA) light, which helps to slow down the growth of skin cells and reduce inflammation.
• Testred · Oncology
• Optipranolol · Cardiovascular
• Cesamet · Other
• Macugen · Ophthalmology
• Miebo · Ophthalmology
  Miebo works by mimicking the natural oils in the eyes to help maintain moisture.
• Elidel · Immunology
  Elidel works by inhibiting calcineurin, a protein that helps activate T-cells, which are involved in the allergic response.
• Dermatop · Oncology
• Mysoline · Metabolic
• Xenazine · Metabolic
  Xenazine works by blocking the reuptake of dopamine and other neurotransmitters into synaptic vesicles, reducing their release and alleviating symptoms of Huntington's chorea.
• Retin-A · Oncology
  Tretinoin works by binding to and activating nuclear receptors, which helps to regulate cell growth and differentiation.
• Syprine · Oncology
• Visudyne · Cardiovascular
  Visudyne selectively binds to neovascular tissue, which is then activated by light to induce a phototoxic reaction.

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• Bausch Health Companies Inc. portfolio CI brief
• Bausch Health Companies Inc. pipeline updates RSS