What are TYK2 inhibitor drugs?

TYK2 inhibitor drugs are pharmacologic agents that share a common mechanism (typically targeting TYK2 (tyrosine kinase 2)). 0 are currently marketed, with 8 more in clinical development.

TYK2 inhibitor

0 marketed 7 in Phase 3 1 in Phase 2

This page covers all TYK2 inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting TYK2 (tyrosine kinase 2), TYK2.

Targets

TYK2 (tyrosine kinase 2) · TYK2

Phase 3 pipeline (7)

ASP7374 · UMN Pharma Inc. · Immunology
ASP7374 is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses inflammatory signaling pathways involved in immune-mediated diseases.
GSK2340272A · GlaxoSmithKline · Immunology
GSK2340272A is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses inflammatory signaling pathways involved in immune-mediated diseases.
GSK5764227 · GlaxoSmithKline · Immunology
GSK5764227 is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses inflammatory signaling pathways involved in immune-mediated diseases.
Placebo to match deucravacitinib · Takeda · Immunology
Deucravacitinib is a small molecule that acts as a selective tyrosine kinase 2 (TYK2) inhibitor.
GSK2340273A · GlaxoSmithKline · Immunology
GSK2340273A is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses JAK-STAT signaling in immune cells to reduce inflammatory responses.
GSK2340274A · GlaxoSmithKline · Immunology
GSK2340274A is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses inflammatory signaling pathways involved in immune-mediated diseases.
GSK3511294 · GlaxoSmithKline · Immunology
GSK3511294 is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses inflammatory signaling pathways involved in immune-mediated diseases.

Phase 2 pipeline (1)

GSK3389404 · GlaxoSmithKline · Immunology
GSK3389404 is a selective inhibitor of TYK2 (tyrosine kinase 2) that suppresses JAK-STAT signaling in immune cells to reduce inflammatory responses.