What are TRPV1 antagonist drugs?

TRPV1 antagonist drugs are pharmacologic agents that share a common mechanism (typically targeting TRPV1). 0 are currently marketed, with 4 more in clinical development.

TRPV1 antagonist

0 marketed 3 in Phase 3 1 in Phase 2

This page covers all TRPV1 antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting TRPV1, TRPV1 (Transient Receptor Potential Vanilloid 1).

Targets

TRPV1 · TRPV1 (Transient Receptor Potential Vanilloid 1)

Phase 3 pipeline (3)

KPS-0373, High dose · Kissei Pharmaceutical Co., Ltd. · Pain Management
KPS-0373 is a selective TRPV1 antagonist that blocks pain signaling through the transient receptor potential vanilloid 1 channel.
TV-44749 · Teva Branded Pharmaceutical Products R&D LLC · Pain Management
TV-44749 is a selective inhibitor of transient receptor potential vanilloid 1 (TRPV1) that reduces pain signaling by blocking capsaicin-sensitive nociceptors.
CG5503 IR · Grünenthal GmbH · Pain Management
CG5503 is a selective inhibitor of transient receptor potential vanilloid 1 (TRPV1) that reduces pain signaling by blocking capsaicin-sensitive nociceptors.

Phase 2 pipeline (1)

AGN-210669 · Allergan · Pain Management
AGN-210669 is a selective inhibitor of the transient receptor potential vanilloid 1 (TRPV1) channel that reduces pain signaling in sensory neurons.