What are Taxane and platinum-based chemotherapy drugs?

Taxane and platinum-based chemotherapy drugs are pharmacologic agents that share a common mechanism (typically targeting Microtubules and DNA). 0 are currently marketed, with 3 more in clinical development.

Taxane and platinum-based chemotherapy

0 marketed 3 in Phase 3

This page covers all Taxane and platinum-based chemotherapy drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Microtubules and DNA.

Targets

Microtubules and DNA

Phase 3 pipeline (3)

docetaxel and carboplatin · Sanofi · Oncology
Docetaxel is a microtubule inhibitor that disrupts cell division, while carboplatin is a platinum-based alkylating agent that cross-links DNA, both leading to cell death.
paclitaxel plus carboplatin · Immatics US, Inc. · Oncology
Paclitaxel works by inhibiting cell division, while carboplatin interferes with DNA repair, both leading to cell death in rapidly dividing cancer cells.
docetaxel - cisplatin - 5-fluorouracil · Gruppo Oncologico del Nord-Ovest · Oncology
Docetaxel inhibits microtubule dynamics, disrupting cell division, while cisplatin induces DNA crosslinks, and 5-fluorouracil inhibits thymidylate synthase.