Serotonin-1b and Serotonin-1d Receptor Agonist

This page covers all Serotonin-1b and Serotonin-1d Receptor Agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting 5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 1B, 5-HT 1B/1D receptors.

Targets

5-hydroxytryptamine receptor 1D · 5-hydroxytryptamine receptor 1B · 5-HT 1B/1D receptors

Marketed (6)

• Relpax · Upjohn · Neuroscience
• Imitrex · GSK · Neuroscience
  Imitrex works by binding to serotonin receptors in the brain, specifically the 5-HT1D subtype, to constrict blood vessels and block pain pathways.
• Frova · Endo Operations · Neuroscience
  Frova works by binding to serotonin receptors in the brain to relieve migraine symptoms.
• Maxalt · Gensco · Neuroscience
  Maxalt works by binding to serotonin receptors in the brain to relieve migraine pain.
• Axert · Johnson & Johnson · Neuroscience
  Axert works by binding to serotonin receptors in the brain to relieve migraine pain.
• Amerge · GSK · Neuroscience
  Naratriptan treats migraines by binding to 5-HT 1B/1D receptors, causing cranial vessel constriction and inhibiting neuropeptide release.