What are SARS-CoV-2 main protease inhibitor drugs?

SARS-CoV-2 main protease inhibitor drugs are pharmacologic agents that share a common mechanism (typically targeting SARS-CoV-2 main protease). 2 are currently marketed, with 13 more in clinical development.

What are the marketed SARS-CoV-2 main protease inhibitor drugs?

Marketed SARS-CoV-2 main protease inhibitor drugs include Ximingting Tablet, (E) BQ-V14.

SARS-CoV-2 main protease inhibitor

2 marketed 7 in Phase 3 6 in Phase 2

This page covers all SARS-CoV-2 main protease inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting SARS-CoV-2 main protease.

Targets

SARS-CoV-2 main protease

Marketed (2)

Ximingting Tablet · Peking Union Medical College Hospital · Infectious Disease
Ximingting Tablet is a small molecule that inhibits the SARS-CoV-2 main protease.
(E) BQ-V14 · National Taiwan University Hospital · Infectious Diseases
BQ-V14 is a small molecule that targets the SARS-CoV-2 main protease.

Phase 3 pipeline (7)

AG2001 · Ahn-Gook Pharmaceuticals Co.,Ltd · Infectious Diseases
AG2001 is a small molecule that targets the SARS-CoV-2 main protease.
wIPV · Beijing Minhai Biotechnology Co., Ltd · Infectious Diseases
WIPV is a small molecule targeting the SARS-CoV-2 main protease.
WPV01 · Westlake Pharmaceuticals (Hangzhou) Co., Ltd. · Infectious Diseases
WPV01 is a small molecule drug that targets the SARS-CoV-2 main protease.
NUCS · IRCCS San Raffaele · Infectious Diseases
NUCS is a small molecule that targets the SARS-CoV-2 main protease.
TTYP01 tablets · Shanghai Auzone Biological Technology Co., Ltd. · Infectious Diseases
TTYP01 tablets are a small molecule drug that targets the SARS-CoV-2 main protease.
XC221 · RSV Therapeutics LLC · Infectious Disease
XC221 is a small molecule that inhibits the activity of the SARS-CoV-2 main protease.
AD-203 · Addpharma Inc. · Infectious Disease
AD-203 is a small molecule that targets the SARS-CoV-2 main protease.

Phase 2 pipeline (6)

ETH47 · Ethris GmbH · Infectious Diseases
ETH47 is a small molecule that targets the SARS-CoV-2 main protease.
GRT-C901 · Seattle Project Corporation · Infectious Diseases
GRT-C901 is a small molecule that targets the SARS-CoV-2 main protease.
Flotufolastat F18 · Icahn School of Medicine at Mount Sinai · Infectious Disease
Flotufolastat F18 is a small molecule that targets the SARS-CoV-2 main protease.
CDI-31244 · Cocrystal Pharma, Inc. · Infectious Diseases
CDI-31244 is a small molecule inhibitor targeting the SARS-CoV-2 main protease.
BTA798 · Biota Scientific Management Pty Ltd · Infectious Diseases
BTA798 is a small molecule inhibitor of the SARS-CoV-2 main protease.
CC-42344 · Cocrystal Pharma, Inc. · Infectious Disease
CC-42344 is a small molecule inhibitor of the SARS-CoV-2 main protease.