Last reviewed · How we verify

(E) BQ-V14

National Taiwan University Hospital · FDA-approved active Small molecule

BQ-V14 is a small molecule that targets the SARS-CoV-2 main protease.

BQ-V14 is a small molecule that targets the SARS-CoV-2 main protease. Used for Treatment of COVID-19.

At a glance

Generic name(E) BQ-V14
SponsorNational Taiwan University Hospital
Drug classSARS-CoV-2 main protease inhibitor
TargetSARS-CoV-2 main protease
ModalitySmall molecule
Therapeutic areaInfectious Diseases
PhaseFDA-approved

Mechanism of action

BQ-V14 works by inhibiting the main protease of SARS-CoV-2, which is essential for the virus's replication. This inhibition prevents the virus from producing new viral particles, thereby reducing the severity of the infection.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results