Pleuromutilin antibiotic

This page covers all Pleuromutilin antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial 50S ribosomal subunit.

Targets

Bacterial 50S ribosomal subunit

Marketed (2)

• Retapamulin (Altabax) · The University of Texas Health Science Center, Houston · Infectious Disease / Dermatology
  Retapamulin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing bacterial growth.
• Altabax (R) · St. Luke's-Roosevelt Hospital Center · Infectious Disease / Dermatology
  Retapamulin is a bacterial protein synthesis inhibitor that binds to the bacterial ribosome to prevent bacterial growth.

Phase 3 pipeline (1)

• Retpamulin Ointment, 1% · Stiefel, a GSK Company · Infectious Disease / Dermatology
  Retpamulin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation and bacterial growth.