Platinum-based chemotherapeutic agent and thymidylate synthase inhibitor
This page covers all Platinum-based chemotherapeutic agent and thymidylate synthase inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Thymidylate synthase, DNA.
Targets
Phase 3 pipeline (1)
- oxaliplatin , fluorouracil, and leucovorin · Sun Yat-sen University · Oncology
Oxaliplatin, fluorouracil, and leucovorin work together to inhibit thymidylate synthase and DNA synthesis, leading to cell death in rapidly dividing cancer cells.
Phase 2 pipeline (1)
- Adjuvant FOLFOX · Asan Medical Center · Oncology
Oxaliplatin and 5-fluorouracil inhibit DNA replication and transcription by cross-linking DNA and interfering with thymidylate synthase.
Patent intelligence
- platinum based chemotherapeutic agent and thymidylate synthase inhibitor patent landscape — aggregated cliff calendar, attackable patents, originator estates