NMDA receptor modulator

This page covers all NMDA receptor modulator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting NMDA receptor (glutamate); GABA system, NMDA receptor (N-methyl-D-aspartate receptor).

Targets

NMDA receptor (glutamate); GABA system · NMDA receptor (N-methyl-D-aspartate receptor)

Marketed (1)

• acamprosate (Campral) · University of North Carolina, Chapel Hill · Psychiatry / Addiction Medicine
  Acamprosate modulates glutamate and GABA neurotransmission to restore neurochemical balance disrupted by chronic alcohol use.

Phase 3 pipeline (1)

• Placebo-matching Rapastinel · Naurex, Inc, an affiliate of Allergan plc · Psychiatry/Neurology
  Rapastinel is an NMDA receptor modulator that enhances glutamatergic neurotransmission by potentiating NMDA receptor function to improve cognitive and psychiatric symptoms.