Neuroprotective agent

This page covers all Neuroprotective agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting NMDA receptor, mitochondrial membrane, monoamine oxidase, NMDA receptor, Mitochondrial function modulator (non-specific).

Targets

NMDA receptor, mitochondrial membrane, monoamine oxidase · NMDA receptor · Mitochondrial function modulator (non-specific)

Marketed (1)

• Butylphthalide Soft Capsules · Peking Union Medical College Hospital · Neurology
  Butylphthalide protects brain cells by improving mitochondrial function and reducing oxidative stress and inflammation following ischemic stroke.

Phase 3 pipeline (4)

• DMB-I (INN: Latrepirdine) · Bigespas LTD · Neurology
  Latrepirdine is a neuroprotective agent that modulates mitochondrial function and reduces neuronal excitotoxicity through multiple pathways including NMDA receptor antagonism and monoamine oxidase inhibition.
• Cattle Encephalon Glycoside and Ignotin · Rong Hu, MD · Neurology
  Cattle encephalon glycoside and ignotin is a neuroprotective agent derived from bovine brain tissue that enhances neuronal metabolism and cerebral blood flow.
• Xaliproden (SR57746A) · Sanofi · Neurology
  Xaliproden acts as a neuroprotective agent by modulating the activity of the NMDA receptor.
• Butylphthalide soft capsule · Capital Medical University · Neurology
  Butylphthalide protects brain cells by improving mitochondrial function and reducing oxidative stress and inflammation following ischemic stroke.