Natriuretic peptide

This page covers all Natriuretic peptide drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Natriuretic peptide receptor-A (NPR-A), Atrial natriuretic peptide receptor 1.

Targets

Natriuretic peptide receptor-A (NPR-A) · Atrial natriuretic peptide receptor 1

Marketed (5)

• Carperitide heart failure therapy · Nara Medical University · Cardiovascular
  Carperitide is a recombinant human atrial natriuretic peptide (ANP) that binds to natriuretic peptide receptors to promote vasodilation, reduce cardiac preload and afterload, and improve cardiac output in heart failure.
• rhBNP · LI ZHAO · Cardiovascular
  rhBNP (recombinant human B-type natriuretic peptide) mimics the body's natural natriuretic peptide to promote vasodilation, reduce cardiac preload and afterload, and improve hemodynamics in acute decompensated heart failure.
• recombinant human BNP(1-32) · VA Office of Research and Development · Cardiovascular
  Recombinant human BNP(1-32) is a truncated B-type natriuretic peptide that activates natriuretic peptide receptors to promote vasodilation, reduce cardiac preload and afterload, and inhibit the renin-angiotensin-aldosterone system.
• Nesiritide (Natrecor) · M.D. Anderson Cancer Center · Cardiovascular
  Nesiritide is a recombinant B-type natriuretic peptide that binds to natriuretic peptide receptors, promoting vasodilation and sodium excretion to reduce cardiac preload and afterload.
• Natrecor · Scios Llc · Cardiovascular

Phase 3 pipeline (1)

• Natrecor (nesiritide) · Scios, Inc. · Cardiovascular
  Nesiritide is a recombinant B-type natriuretic peptide that binds to natriuretic peptide receptors to promote vasodilation, reduce cardiac preload and afterload, and increase sodium excretion.