Monoamine Oxidase Inhibitors

This page covers all Monoamine Oxidase Inhibitors drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, monoamine oxidase A.

Targets

Amine oxidase [flavin-containing] A · Amine oxidase [flavin-containing] B · monoamine oxidase A · 5-hydroxytryptamine receptor 6 · Monoamine oxidase · Mitochondrial electron transport chain; monoamine oxidase; methemoglobin reductase · monoamine oxidase A and B · Monoamine oxidase (MAO) · Mitochondrial electron transport chain; Monoamine oxidase · Monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B)

Marketed (14)

• Humoryl · Neuroscience
• Parnate · Advanz · Neuroscience
  Parnate works by blocking an enzyme that breaks down certain neurotransmitters, allowing them to stay in the brain longer.
• B4 · Breath of Life International Pharma Ltd · Psychiatry
  B4 is a medication that works by inhibiting the action of a specific enzyme.
• Nardil · Pfizer · Neuroscience
• Actomol · Neuroscience
• Azilect · Teva · Metabolic
• Selegiline Hydrochloride · Somerset · Neuroscience
• Low dose oxelidine group · The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Psychiatry/Neurology
  Low-dose oxelidine acts as a monoamine oxidase inhibitor to increase neurotransmitter levels in the central nervous system.
• Methylene blue (1%) · University Hospital, Strasbourg, France · Multiple (Toxicology, Psychiatry, Infectious Disease, Hematology)
  Methylene blue acts as a redox agent and monoamine oxidase inhibitor, helping to restore cellular electron transport and reduce oxidative stress.
• Auromid · Neuroscience
• Nardil · Pfizer · Neuroscience
• No Lutinus + transfer day 6 · Anja Bisgaard Pinborg · Psychiatry
  No Lutinus is a medication that works by inhibiting the action of certain enzymes involved in the breakdown of tryptophan.
• Furazol · Takeda · Neuroscience
• Provayblue · Rare Disease
  Provayblue works by inhibiting the enzyme amine oxidase [flavin-containing] A, which is involved in the breakdown of certain amines in the body.

Phase 3 pipeline (4)

• FS MDPI · Teva Branded Pharmaceutical Products R&D, Inc. · Psychiatry/Neurology
  FS MDPI is a monoamine oxidase inhibitor that increases levels of dopamine, norepinephrine, and serotonin in the central nervous system.
• SPD476 (2.4 g) · Shire · Psychiatry/Neurology
  SPD476 is a monoamine oxidase inhibitor that increases levels of dopamine, norepinephrine, and serotonin in the central nervous system.
• Intravenous methylene blue administration · Seoul National University Hospital · Neurology / Psychiatry / Critical Care
  Methylene blue acts as a redox agent and monoamine oxidase inhibitor that reduces oxidative stress and modulates mitochondrial function.
• SPD503-AM · Shire · Psychiatry/Neurology
  SPD503-AM is a monoamine oxidase inhibitor that increases levels of dopamine, norepinephrine, and serotonin in the central nervous system.

Phase 2 pipeline (4)

• Regulton · Neuroscience
  Regulton works by inhibiting the enzyme monoamine oxidase, which breaks down certain neurotransmitters in the brain.
• Iprazid · Neuroscience
  Iproniazid works by blocking the enzyme that breaks down certain neurotransmitters, allowing their levels to increase in the brain.
• Iproclozid · Neuroscience
  Iproclozide works by blocking the enzyme that breaks down certain neurotransmitters in the brain, allowing their levels to increase and improve mood.
• Methylene blue infusion · Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva · Oncology
  A monoamine oxidase inhibitor

Phase 1 pipeline (1)

• 11C-L-deprenyl-D2 · Hoffmann-La Roche · Neurology
  Selective norepinephrine reuptake inhibitor