Last reviewed 2026-05-14 · How we verify

11C-L-deprenyl-D2

Hoffmann-La Roche · Phase 1 active Small molecule

11C-L-deprenyl-D2 is a Monoamine oxidase inhibitor Small molecule drug developed by Hoffmann-La Roche. It is currently in Phase 1 development for Depression.

Selective norepinephrine reuptake inhibitor

Selective norepinephrine reuptake inhibitor Used for Depression.

At a glance

Generic name	11C-L-deprenyl-D2
Sponsor	Hoffmann-La Roche
Drug class	Monoamine oxidase inhibitor
Target	Monoamine oxidase B
Modality	Small molecule
Therapeutic area	Neurology
Phase	Phase 1

Mechanism of action

11C-L-deprenyl-D2 is a radiolabeled derivative of the selective norepinephrine reuptake inhibitor deprenyl, which is used to study the brain's norepinephrine system.

Approved indications

Depression

Common side effects

No common side effects on file.

Key clinical trials

A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers (PHASE1)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

11C-L-deprenyl-D2 CI brief — competitive landscape report
11C-L-deprenyl-D2 updates RSS · CI watch RSS
Hoffmann-La Roche portfolio CI

Frequently asked questions about 11C-L-deprenyl-D2

What is 11C-L-deprenyl-D2?

11C-L-deprenyl-D2 is a Monoamine oxidase inhibitor drug developed by Hoffmann-La Roche, indicated for Depression.

How does 11C-L-deprenyl-D2 work?

Selective norepinephrine reuptake inhibitor

What is 11C-L-deprenyl-D2 used for?

11C-L-deprenyl-D2 is indicated for Depression.

Who makes 11C-L-deprenyl-D2?

11C-L-deprenyl-D2 is developed by Hoffmann-La Roche (see full Hoffmann-La Roche pipeline at /company/roche).

What drug class is 11C-L-deprenyl-D2 in?

11C-L-deprenyl-D2 belongs to the Monoamine oxidase inhibitor class. See all Monoamine oxidase inhibitor drugs at /class/monoamine-oxidase-inhibitor.

What development phase is 11C-L-deprenyl-D2 in?

11C-L-deprenyl-D2 is in Phase 1.

What does 11C-L-deprenyl-D2 target?

11C-L-deprenyl-D2 targets Monoamine oxidase B and is a Monoamine oxidase inhibitor.

Drug class: All Monoamine oxidase inhibitor drugs
Target: All drugs targeting Monoamine oxidase B
Manufacturer: Hoffmann-La Roche — full pipeline
Therapeutic area: All drugs in Neurology
Indication: Drugs for Depression
Compare: 11C-L-deprenyl-D2 vs similar drugs
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