Nucleotide reverse transcriptase inhibitor (microbicide)

This page covers all Nucleotide reverse transcriptase inhibitor (microbicide) drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting HIV reverse transcriptase, gp120.

Targets

HIV reverse transcriptase · gp120

Marketed (1)

• Vaginal TFV Gel · University of Washington · Infectious Disease / HIV Prevention
  Tenofovir (TFV) gel applied vaginally blocks HIV reverse transcriptase to prevent sexual transmission of HIV.

Phase 3 pipeline (1)

• PRO 2000/5 Gel · National Institute of Allergy and Infectious Diseases (NIAID) · Infectious Diseases
  PRO 2000/5 Gel is a microbicide that prevents HIV-1 transmission by inhibiting viral entry into host cells.

Phase 2 pipeline (1)

• Drug: BufferGel® with diaphragm · ReProtect Inc · Infectious Disease / Sexual Health
  BufferGel is a vaginal microbicide gel that buffers vaginal pH to create an acidic environment hostile to HIV and other sexually transmitted pathogens, used in conjunction with a diaphragm for contraceptive and prophylactic protection.

Patent intelligence

• microbicide patent landscape — aggregated cliff calendar, attackable patents, originator estates