What are Gabapentinoid drugs?

Gabapentinoid drugs are pharmacologic agents that share a common mechanism (typically targeting Alpha-2-delta-1 subunit of voltage-gated calcium channels). 0 are currently marketed, with 2 more in clinical development.

Gabapentinoid

0 marketed 2 in Phase 3

This page covers all Gabapentinoid drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Alpha-2-delta-1 subunit of voltage-gated calcium channels.

Targets

Alpha-2-delta-1 subunit of voltage-gated calcium channels

Phase 3 pipeline (2)

Pregabalin add-on therapy · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Neurology
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
Placebo matched with pregabalin · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Neurology
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.