What are Estrogen replacement therapy drugs?

Estrogen replacement therapy drugs are pharmacologic agents that share a common mechanism (typically targeting Estrogen receptors (nuclear receptors)). 6 are currently marketed, with 4 more in clinical development.

What are the marketed Estrogen replacement therapy drugs?

Marketed Estrogen replacement therapy drugs include Premarin, Premarin, Premarin, Estradiol vaginal cream, Estrace 0.01% Vaginal Cream, Estradiol patch.

Estrogen replacement therapy

6 marketed 4 in Phase 3

This page covers all Estrogen replacement therapy drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Estrogen receptors (nuclear receptors), Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ).

Targets

Estrogen receptors (nuclear receptors) · Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)

Marketed (6)

Premarin · Pfizer · Metabolic
Conjugated estrogens bind to nuclear estrogen receptors in estrogen-responsive tissues, modulating gonadotropin secretion and reducing elevated LH and FSH in postmenopausal women.
Premarin · Pfizer
Conjugated estrogens bind to nuclear estrogen receptors in estrogen-responsive tissues, modulating gonadotropin secretion and reducing elevated LH and FSH levels in postmenopausal women.
Premarin · Pfizer
Conjugated estrogens bind to nuclear estrogen receptors in estrogen-responsive tissues, modulating gonadotropin secretion and reducing elevated LH and FSH levels in postmenopausal women.
Estradiol vaginal cream · CONRAD · Gynecology / Endocrinology
Estradiol vaginal cream delivers the hormone estradiol directly to vaginal tissues to restore local estrogen levels and relieve menopausal vaginal symptoms.
Estrace 0.01% Vaginal Cream · University of California, Irvine · Gynecology / Endocrinology
Estrace vaginal cream delivers estradiol directly to vaginal tissues to restore estrogen levels and relieve symptoms of vaginal atrophy and menopausal urogenital changes.
Estradiol patch · University of Virginia · Endocrinology / Women's Health
Estradiol patch delivers estrogen through the skin to replace or supplement endogenous estrogen levels.

Phase 3 pipeline (4)

Estrace® 0.01% cream · Mylan Pharmaceuticals Inc · Gynecology / Endocrinology
Estrace cream delivers estradiol, a natural estrogen, directly to vaginal and vulvar tissues to relieve symptoms of atrophic vaginitis and urogenital atrophy.
Vaginal Estrogen - Daily · Queen's University · Women's Health
Estrogen replacement therapy to alleviate menopausal symptoms.
Vaginal conjugated estrogen cream 0.5gm · TriHealth Inc. · Women's Health
Estrogen replacement therapy to alleviate menopausal symptoms.
Vaginal conjugated estrogen cream 1.0gm · TriHealth Inc. · Women's Health
Estrogen replacement therapy to alleviate menopausal symptoms.