What are Enzyme drugs?

Enzyme drugs are pharmacologic agents that share a common mechanism (typically targeting Asparagine). 2 are currently marketed, with 2 more in clinical development.

What are the marketed Enzyme drugs?

Marketed Enzyme drugs include recombinant asparaginase, Erwinia asparaginase.

Enzyme

2 marketed 2 in Phase 3

This page covers all Enzyme drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Asparagine, Deoxyribonuclease, Ribonuclease inhibitor.

Targets

Asparagine · Deoxyribonuclease, Ribonuclease inhibitor

Marketed (2)

recombinant asparaginase · medac GmbH · Oncology
Recombinant asparaginase depletes the amino acid asparagine from the bloodstream, starving asparagine-dependent leukemic cells of an essential nutrient required for protein synthesis.
Erwinia asparaginase · Andrew E. Place, MD · Oncology
Erwinia asparaginase depletes the amino acid asparagine in the bloodstream, starving leukemic cells that cannot synthesize their own asparagine.

Phase 3 pipeline (2)

E. coli Asparaginase · Dana-Farber Cancer Institute · Oncology
E. coli asparaginase depletes the amino acid asparagine in the bloodstream, starving leukemic cells that cannot synthesize their own asparagine.
Wobe-Mugos E · Medsearch · Respiratory
Wobe-Mugos E is a combination of a deoxyribonuclease and a ribonuclease inhibitor.