Dual endothelin receptor antagonist

This page covers all Dual endothelin receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting ETA and ETB receptors.

Targets

ETA and ETB receptors

Phase 3 pipeline (1)

• Macitentan Group · University of Giessen · Cardiovascular
  Macitentan is a dual endothelin receptor antagonist that blocks both ETA and ETB receptors to reduce pulmonary vascular resistance and improve exercise capacity in pulmonary arterial hypertension.