Direct Factor Xa inhibitor

This page covers all Direct Factor Xa inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Factor Xa, Factor Xa (FXa).

Targets

Factor Xa · Factor Xa (FXa)

Marketed (8)

• rivaroxaban (10mg) · Chang Gung Memorial Hospital · Cardiovascular
  Rivaroxaban is a direct Factor Xa inhibitor that blocks a key enzyme in the blood coagulation cascade, preventing thrombin generation and clot formation.
• Apixaban 2.5 milligram · McMaster University · Cardiovascular
  Apixaban is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent blood clot formation.
• Oroxid® · Charles University, Czech Republic · Cardiovascular
  Oroxid is an oral anticoagulant that inhibits Factor Xa in the coagulation cascade to prevent thrombus formation.
• Rivaroxaban 10 milligram Oral Tablet · Florida Orthopaedic Institute · Cardiovascular
  Rivaroxaban is a direct Factor Xa inhibitor that blocks a key enzyme in the blood coagulation cascade, preventing thrombin generation and clot formation.
• Xarelto · Johnson & Johnson · Oncology
  Selective FXa inhibitor that decreases thrombin generation without requiring cofactors.
• Apixaban single dose · Universitaire Ziekenhuizen KU Leuven · Cardiovascular
  Apixaban is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent blood clot formation.
• Rivaroxaban Oral Tablet · Swiss Paraplegic Research, Nottwil · Cardiovascular
  Rivaroxaban is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent blood clot formation.
• Rivaroxaban (Xarelto) · University of Michigan · Cardiovascular
  Rivaroxaban is a direct Factor Xa inhibitor that blocks a key enzyme in the blood coagulation cascade, preventing thrombin generation and clot formation.

Phase 3 pipeline (5)

• Orafang Tab · Taejoon Pharmaceutical Co., Ltd. · Cardiovascular
  Orafang is an oral anticoagulant that inhibits Factor Xa in the coagulation cascade to prevent thrombus formation.
• Rivaroxaban 10 Milligrams · Ahmed AbdelMoneim Hassan Ali · Cardiovascular
  Rivaroxaban is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent blood clot formation.
• Anticoagulant treatment Rivaroxaban · Rennes University Hospital · Cardiovascular
  Rivaroxaban is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent blood clot formation.
• DU-176b (edoxaban) · Daiichi Sankyo Co., Ltd. · Cardiovascular
  Edoxaban is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent blood clot formation.
• BAY 59-7939 · Bayer · Cardiovascular
  BAY 59-7939 is a direct Factor Xa inhibitor that blocks the coagulation cascade to prevent thrombus formation.