Class III antiarrhythmic agent

This page covers all Class III antiarrhythmic agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Potassium channels (hERG), sodium channels, beta-adrenergic receptors, calcium channels, Potassium channels, sodium channels, calcium channels, beta-adrenergic receptors, Potassium channels (hERG); also sodium channels, beta-adrenergic receptors, and calcium channels.

Targets

Potassium channels (hERG), sodium channels, beta-adrenergic receptors, calcium channels · Potassium channels, sodium channels, calcium channels, beta-adrenergic receptors · Potassium channels (hERG); also sodium channels, beta-adrenergic receptors, and calcium channels · Potassium channels (hERG), sodium channels, L-type calcium channels, beta-adrenergic receptors · Potassium channels (hERG), sodium channels, calcium channels, beta-adrenergic receptors · Delayed rectifier potassium channels (hERG); sodium channels · Potassium channels (hERG, IKr); also sodium channels, calcium channels, and beta-adrenergic receptors

Marketed (8)

• Intravenous amiodarone(2) · Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud · Cardiovascular
  Intravenous amiodarone is a Class III antiarrhythmic agent that blocks potassium channels and prolongs the action potential duration and refractory period to restore normal heart rhythm.
• amiodarone amiodarone · National Heart, Lung, and Blood Institute (NHLBI) · Cardiovascular
  Amiodarone blocks multiple cardiac ion channels (sodium, potassium, calcium, and beta-adrenergic) to slow electrical conduction and suppress abnormal heart rhythms.
• Intravenous amiodarone(1) · Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud · Cardiovascular
  Intravenous amiodarone blocks multiple cardiac ion channels (sodium, potassium, calcium, and beta-adrenergic) to suppress abnormal electrical activity and restore normal heart rhythm.
• Amiodarone i.v. · Charles University, Czech Republic · Cardiovascular
  Amiodarone is a Class III antiarrhythmic that blocks potassium channels to prolong the action potential and refractory period, with additional effects on sodium, calcium, and beta-adrenergic channels.
• Amiodarone Pill · Our Lady of the Lake Hospital · Cardiovascular
  Amiodarone blocks multiple cardiac ion channels (sodium, potassium, calcium, and beta-adrenergic) to slow electrical conduction and suppress abnormal heart rhythms.
• (A) T-V14 · National Taiwan University Hospital · Cardiovascular
  T-V14 is a medication used to treat atrial fibrillation.
• iv Amiodarone · Hospital General Universitario Gregorio Marañon · Cardiovascular
  Amiodarone blocks cardiac potassium, sodium, calcium, and beta-adrenergic channels to slow electrical conduction and suppress arrhythmias.
• Corvert (Ibutilide) · Medical University of Vienna · Cardiovascular
  Ibutilide is a Class III antiarrhythmic agent that prolongs the cardiac action potential duration by blocking potassium channels and activating inward sodium current.

Phase 3 pipeline (1)

• Amiodarone Injectable Solution · Hippocration General Hospital · Cardiovascular
  Amiodarone is a Class III antiarrhythmic agent that blocks potassium channels and prolongs the action potential duration and refractory period to restore normal heart rhythm.