Chloride channel activator

This page covers all Chloride channel activator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting ClC-2 chloride channel.

Targets

ClC-2 chloride channel

Marketed (1)

• Amitiza (Lubiprostone) · Brooke Army Medical Center · Gastroenterology
  Lubiprostone activates ClC-2 chloride channels in the intestinal epithelium to increase fluid secretion into the bowel lumen, promoting stool passage.

Phase 3 pipeline (1)

• Cohort 1: Lubiprostone Capsule, Fasted · Sucampo Pharma Americas, LLC · Gastroenterology
  Lubiprostone activates ClC-2 chloride channels in the intestinal epithelium to increase intestinal fluid secretion and promote bowel motility.