centrally acting muscle relaxant with anticholinergic properties

This page covers all centrally acting muscle relaxant with anticholinergic properties drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting reticular formation (brain stem), Monoamine oxidase; noradrenergic and serotonergic pathways.

Targets

reticular formation (brain stem) · Monoamine oxidase; noradrenergic and serotonergic pathways

Marketed (2)

• Norgesic · Endo · Immunology
  Orphenadrine citrate centrally acts on brain stem to selectively block facilitatory reticular functions.
• Flexeril Oral Product · University of California, Davis · Neurology / Musculoskeletal
  Flexeril (cyclobenzaprine) is a centrally acting muscle relaxant that reduces muscle spasms by depressing activity in the brainstem.

Phase 3 pipeline (2)

• Tolperisone Hydrochloride · Neurana Pharmaceuticals, Inc. · Neurology
  Tolperisone hydrochloride is a centrally acting muscle relaxant that reduces muscle tone and spasticity by modulating neural pathways in the spinal cord.
• Eperisone hydrochloride · Eisai Co., Ltd. · Neurology / Musculoskeletal
  Eperisone hydrochloride is a muscle relaxant that reduces muscle tension by inhibiting monoamine oxidase and enhancing noradrenergic and serotonergic neurotransmission in the central nervous system.