Cannabinoid

This page covers all Cannabinoid drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Multiple targets including CB1/CB2 (allosteric modulation), 5-HT1A receptor, TRPV1 channel, Multiple (5-HT1A, TRPV1, CB1, CB2, glycine receptors), CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor (multiple targets).

Targets

Multiple targets including CB1/CB2 (allosteric modulation), 5-HT1A receptor, TRPV1 channel · Multiple (5-HT1A, TRPV1, CB1, CB2, glycine receptors) · CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor (multiple targets) · 5-HT1A, TRPV1, GPR55, CB1 (allosteric), CB2 (allosteric) · CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor · CB1 receptor · Multiple targets including TRPV1, 5-HT1A, GPR55, and endocannabinoid system modulation · CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 channel · CB1 and CB2 receptors · CB2 receptor

Marketed (4)

• Cannabidiol Oral Product · University of Connecticut · Neurology, Psychiatry, Immunology
  Cannabidiol (CBD) is a non-intoxicating cannabinoid that modulates multiple molecular targets including serotonin receptors, TRPV1 channels, and endocannabinoid signaling to produce anti-inflammatory, anxiolytic, and anticonvulsant effects.
• Cannabidiol oral oil · Hôpital le Vinatier · Neurology/Psychiatry
  Cannabidiol modulates endocannabinoid signaling and multiple other pathways to produce anxiolytic, anti-inflammatory, and neuroprotective effects.
• MediCabilis CBD Oil · Gold Coast Hospital and Health Service · Neurology, Pain Management, Psychiatry
  CBD (cannabidiol) modulates endocannabinoid system signaling and interacts with multiple receptors to produce anti-inflammatory, anxiolytic, and analgesic effects.
• CBD · Stero Biotechs Ltd. · Neurology, Psychiatry, Pain Management, Immunology
  CBD (cannabidiol) modulates endocannabinoid signaling and interacts with multiple receptors including serotonin 5-HT1A, TRPV1, and GPR55 to produce anti-inflammatory, anxiolytic, and analgesic effects.

Phase 3 pipeline (7)

• Placebo Matched to Low-Dose Cannabidiol · Wayne State University · Neurology
  Cannabidiol (CBD) modulates endocannabinoid signaling and multiple receptor systems to produce therapeutic effects.
• SP-102 · Scilex Pharmaceuticals, Inc. · Pain
  SP-102 is a synthetic version of delta-9-tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis.
• Cannabidiol oral solution · University of California, San Diego · Neurology
  Cannabidiol modulates endocannabinoid signaling and multiple other pathways to reduce seizure activity and provide neuroprotective effects.
• Low-Dose Cannabidiol · Wayne State University · Neurology, Psychiatry, Immunology
  Low-dose cannabidiol modulates endocannabinoid signaling and reduces neuroinflammation through CB1/CB2 receptor interactions and non-receptor pathways.
• THC/CBD · Azienda Ospedaliera Universitaria Policlinico "G. Martino" · Pain management
  THC/CBD acts on the CB1 and CB2 receptors in the brain and body.
• ZYN002 - transdermal gel · Zynerba Pharmaceuticals, Inc. · Epilepsy
  ZYN002, a transdermal gel formulation of cannabidiol, is thought to exert its therapeutic effects through its action on the endocannabinoid system.
• Moderate-Dose Cannabidiol · Wayne State University · Neurology, Psychiatry, Immunology
  Cannabidiol modulates endocannabinoid signaling and multiple receptor pathways to produce anti-inflammatory, anxiolytic, and neuroprotective effects.

Phase 2 pipeline (5)

• CBDV Compound · Montefiore Medical Center · Neurology
  CBDV (cannabidivarin) is a non-intoxicating cannabinoid that modulates endocannabinoid signaling and may reduce neuronal hyperexcitability.
• Full-Spectrum Cannabidiol · Staci Gruber, Ph.D. · Neurology
  Cannabidiol acts as a CB1 receptor antagonist
• Cannabis, Medical · OMNI Medical Services, LLC · Pain Management, Neurology, Oncology, Gastroenterology
  Medical cannabis modulates the endocannabinoid system through cannabinoid receptors (CB1 and CB2) to produce therapeutic effects including pain relief, anti-inflammation, and symptom management.
• APH-1501 · Aphios · Pain
  APH-1501 is a cannabinoid-based therapy.
• Avidekel oil · Wolfson Medical Center · Pain management
  Avidekel oil is a cannabis-based medication that works by interacting with the body's endocannabinoid system.