Last reviewed 2026-04-23 · How we verify

THC/CBD

THC/CBD acts on the CB1 and CB2 receptors in the brain and body.

THC/CBD acts on the CB1 and CB2 receptors in the brain and body. Used for Treatment of chemotherapy-induced nausea and vomiting, Management of spasticity associated with multiple sclerosis.

At a glance

Mechanism of action

THC/CBD binds to cannabinoid receptors, which are involved in pain relief, mood regulation, and other physiological processes. This interaction can lead to various therapeutic effects, including pain relief and reduced inflammation.

Approved indications

• Treatment of chemotherapy-induced nausea and vomiting
• Management of spasticity associated with multiple sclerosis

Common side effects

• Dizziness
• Dry mouth
• Fatigue
• Nausea

Key clinical trials

• EFFECTS OF A FULL SPECTRUM CANNABIS EXTRACT WITH DIFFERENT DOSES OF CBD AND THC ON THE MODULATION OF FIBROMYALGIA: A PILOT, MULTICENTER, OPEN LABEL CLINICAL TRIAL (FRIDINHA) (PHASE1, PHASE2)
• Evaluation of Smoked THC and CBD in Men and Women (PHASE1)
• Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment (PHASE2)
• Exploring The Effect Of Cannabidiol On Cannabis Tolerance Using A Novel Vaporiser Device In Heavy Users (Stage 1) (NA)
• Unique Treatment of Oncology Pain in Advanced Cancer (PHASE2)
• Cannabis extrAct in Oncology Patients for the Treatment of TUmor Related Symptom Burden (PHASE2)
• Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain (NA)
• Effects of Hemp-Derived Cannabinoids on Menopause Symptoms (PHASE2)

Primary sources

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