Antifolate antimalarial combination with quinoline antimalarial

This page covers all Antifolate antimalarial combination with quinoline antimalarial drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Plasmodium dihydrofolate reductase, dihydropteroate synthase, and parasite mitochondria.

Targets

Plasmodium dihydrofolate reductase, dihydropteroate synthase, and parasite mitochondria

Phase 3 pipeline (1)

• sulfadoxine pyrimethamine plus piperaquine · London School of Hygiene and Tropical Medicine · Infectious Disease
  This combination drug inhibits parasite folate synthesis (sulfadoxine-pyrimethamine) and disrupts parasite mitochondrial function (piperaquine) to treat malaria.

Patent intelligence

• antifolate antimalarial combination with quinoline antimalarial patent landscape — aggregated cliff calendar, attackable patents, originator estates