Antidote

This page covers all Antidote drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Glutathione levels; reactive metabolite of acetaminophen.

Targets

Glutathione levels; reactive metabolite of acetaminophen

Marketed (3)

• Acetatocobalamin · Respiratory
• Acetadote · Bristol-Myers Squibb · Metabolic
  Acetylcysteine reduces liver injury from acetaminophen overdose by maintaining glutathione levels or providing alternate conjugation substrate.
• Cyanokit · Btg Intl · Metabolic

Phase 3 pipeline (2)

• sodium thiosulfate solution · Xijing Hospital of Digestive Diseases · Toxicology
  Sodium thiosulfate solution works by neutralizing cyanide ions.
• levo-folinic acid · National Cancer Institute, Naples · Oncology
  Levo-folinic acid is a form of folinic acid used to help counteract the toxic effects of methotrexate.