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sodium thiosulfate solution
Sodium thiosulfate solution works by neutralizing cyanide ions.
Sodium thiosulfate solution works by neutralizing cyanide ions. Used for Cyanide poisoning.
At a glance
| Generic name | sodium thiosulfate solution |
|---|---|
| Also known as | STS |
| Sponsor | Xijing Hospital of Digestive Diseases |
| Drug class | Antidote |
| Modality | Small molecule |
| Therapeutic area | Toxicology |
| Phase | Phase 3 |
Mechanism of action
It does this by forming a stable complex with cyanide, which is then excreted from the body. This mechanism is particularly useful in treating cyanide poisoning.
Approved indications
- Cyanide poisoning
Common side effects
- Hypocalcemia
- Hypophosphatemia
- Nausea
- Vomiting
- Diarrhea
Key clinical trials
- Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies (PHASE1)
- Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing (PHASE2)
- Better Evidence and Translation for Calciphylaxis (PHASE3)
- Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods (NA)
- The Effect of Sodium Thiosulfate Eardrops on Hearing Loss in Patients Who Receive Cisplatin Therapy (NA)
- Evaluation of Thiosulfate Enhanced Organ Preservation Solution in Kidney Transplantation (NA)
- Evaluation of Thiosulfate in End Stage Renal Disease and Kidney Transplantation (PHASE1)
- Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- sodium thiosulfate solution CI brief — competitive landscape report
- sodium thiosulfate solution updates RSS · CI watch RSS
- Xijing Hospital of Digestive Diseases portfolio CI