Analgesic
This page covers all Analgesic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting COX enzymes, cyclooxygenase (COX).
Targets
COX enzymes · cyclooxygenase (COX)
Phase 3 pipeline (1)
- paracetamol + caffeine · GlaxoSmithKline · Pain management
Paracetamol acts as a non-selective inhibitor of COX enzymes, reducing prostaglandin synthesis and thereby decreasing pain and fever, while caffeine acts as a stimulant and analgesic.
Phase 1 pipeline (1)
- Acetaminophen solid formulation · Beth Israel Deaconess Medical Center · Pain Management
Acetaminophen exerts its analgesic and antipyretic effects primarily through inhibition of cyclooxygenase (COX) enzymes, leading to reduced prostaglandin synthesis.