Alpha-1 adrenergic receptor antagonist

This page covers all Alpha-1 adrenergic receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Alpha-1 adrenergic receptor.

Targets

Alpha-1 adrenergic receptor

Marketed (5)

• Placebo to Prazosin · Brian J Lipworth · Cardiovascular; Urology; Psychiatry (off-label)
  Prazosin is an alpha-1 adrenergic receptor antagonist that blocks norepinephrine signaling to reduce blood pressure and improve urinary symptoms.
• Doxazosin mysylate GITS · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Cardiovascular; Urology
  Doxazosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow, and also dilates blood vessels to lower blood pressure.
• Doxazosin extended release · University of Arkansas · Cardiovascular, Urology
  Doxazosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow, and also dilates blood vessels to lower blood pressure.
• Doxazosin (drug) · Japan Heart Foundation · Cardiovascular; Urology
  Doxazosin is an alpha-1 adrenergic receptor antagonist that blocks norepinephrine signaling in blood vessels and the prostate, causing vasodilation and smooth muscle relaxation.
• Alpha1 Blocker · Eli Lilly and Company · Cardiovascular, Urology
  Alpha-1 blockers inhibit alpha-1 adrenergic receptors on vascular smooth muscle and the prostate, causing vasodilation and reduced urinary obstruction.

Phase 3 pipeline (6)

• alfuzosin (SL770499) · Sanofi · Urology
  Alfuzosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck, improving urine flow.
• Silodosin capsules Control Group · Shanghai Huilun Pharmaceutical Co., Ltd. · Urology
  Silodosin is an alpha-1 adrenergic receptor antagonist.
• Terazosin (Hytrin) · Hospital Authority, Hong Kong · Cardiovascular
  Terazosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck, improving urine flow and reducing symptoms of benign prostatic hyperplasia.
• Optimized medical BPH treatment · University Hospital, Bordeaux · Urology
  This drug targets the alpha-1 adrenergic receptor to relax smooth muscle in the prostate.
• T.Prazosin · Haffkine Bio-Pharmaceutical Corporation Ltd. · Cardiovascular
  T.Prazosin is an alpha-1 adrenergic receptor antagonist.
• pr Sandoz Tamsulosin · CHU de Quebec-Universite Laval · Urology
  Tamsulosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscles in the prostate and bladder neck, improving urine flow.

Phase 2 pipeline (1)

• Doxazosin Mesylate, Extended Release · San Francisco Veterans Affairs Medical Center · Urology
  Doxazosin mesylate is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck, improving urine flow and reducing symptoms of benign prostatic hyperplasia.