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ziprasidone or olanzapine — Competitive Intelligence Brief
marketed
Atypical antipsychotic
Dopamine D2 receptor; Serotonin 5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
ziprasidone or olanzapine (ziprasidone or olanzapine) — Medical University of Vienna. Both ziprasidone and olanzapine are atypical antipsychotics that block dopamine D2 and serotonin 5-HT2A receptors to reduce psychotic symptoms.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ziprasidone or olanzapine TARGET | ziprasidone or olanzapine | Medical University of Vienna | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Aripiprazole; Quetiapine | Aripiprazole; Quetiapine | Taichung Veterans General Hospital | marketed | Atypical antipsychotic combination | Dopamine D2 receptor; Serotonin 5-HT2A receptor; Serotonin 5-HT1A receptor | |
| Antipsychotic Maintenance | Antipsychotic Maintenance | University College, London | marketed | Antipsychotic (typical or atypical) | Dopamine D2 receptor; serotonin 5-HT2A receptor (varies by specific agent) | |
| Risperidone tablets | Risperidone tablets | Sumitomo Pharma (Suzhou) Co., Ltd. | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Risperidone low dose | Risperidone low dose | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Intramuscular olanzapine, aripiprazole | Intramuscular olanzapine, aripiprazole | Veterans Medical Research Foundation | marketed | Atypical antipsychotic | Dopamine D2 receptor; serotonin 5-HT2A receptor (olanzapine); dopamine D2 partial agonist (aripiprazole) | |
| Standard of Care Oral antipsychotics | Standard of Care Oral antipsychotics | University of Utah | marketed | Antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). ziprasidone or olanzapine — Competitive Intelligence Brief. https://druglandscape.com/ci/ziprasidone-or-olanzapine. Accessed 2026-05-16.
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