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VP16, ATG — Competitive Intelligence Brief
phase 3
Alkylating agent
Topoisomerase II
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
VP16, ATG (VP16, ATG) — St. Anna Kinderkrebsforschung. VP16 is an alkylating agent that works by cross-linking DNA, thereby inhibiting DNA replication and transcription.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| VP16, ATG TARGET | VP16, ATG | St. Anna Kinderkrebsforschung | phase 3 | Alkylating agent | Topoisomerase II | |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Idamycin Pfs | IDARUBICIN HYDROCHLORIDE | marketed | Anthracycline Topoisomerase Inhibitor | DNA, topoisomerase II | 1990-01-01 | |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Cipro | ciprofloxacin | Bayer AG | marketed | Fluoroquinolone antibiotic | DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A | 1987-10-22 |
| Amekrin | AMSACRINE | marketed | amsacrine | DNA topoisomerase 2-beta, Solute carrier family 22 member 1, DNA topoisomerase II | 1987-01-01 | |
| DOXORUBICIN HYDROCHLORIDE | DOXORUBICIN HYDROCHLORIDE | marketed | topoisomerase II | 1974-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Cipro · 11369566 · Formulation · US
- — Cipro · 9603796 · Compound · US
- — Cipro · 9205048 · Method of Use · US
- — Cipro · 9233068 · Formulation · US
- — Cipro · 8318817 · Method of Use · US
- — Cipro · 9220796 · Formulation · US
- — Cipro · 11040004 · Method of Use · US
- — Cipro · 11246863 · Formulation · US
Sponsor landscape (Alkylating agent class)
- Assistance Publique - Hôpitaux de Paris · 2 drugs in this class
- M.D. Anderson Cancer Center · 2 drugs in this class
- Nanfang Hospital, Southern Medical University · 2 drugs in this class
- Asahi Kasei Pharma Corporation · 1 drug in this class
- Baxter · 1 drug in this class
- BeBetter Med Inc · 1 drug in this class
- Astellas Pharma China, Inc. · 1 drug in this class
- Children's Cancer Group, China · 1 drug in this class
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology · 1 drug in this class
- Celyad Oncology SA · 1 drug in this class
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Cite this brief
Drug Landscape (2026). VP16, ATG — Competitive Intelligence Brief. https://druglandscape.com/ci/vp16-atg. Accessed 2026-05-15.
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