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voriconazole (VFEND®) — Competitive Intelligence Brief
phase 3
Azole antifungal
Lanosterol 14α-demethylase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
voriconazole (VFEND®) (voriconazole (VFEND®)) — Pfizer. Voriconazole is an antifungal medication that inhibits the synthesis of ergosterol, an essential component of fungal cell membranes.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| voriconazole (VFEND®) TARGET | voriconazole (VFEND®) | Pfizer | phase 3 | Azole antifungal | Lanosterol 14α-demethylase | |
| Clotrimazole vaginal tablets+ Lactobacillus | Clotrimazole vaginal tablets+ Lactobacillus | Peking University Shenzhen Hospital | marketed | Antifungal + probiotic combination | Fungal lanosterol 14α-demethylase (CYP51); Lactobacillus competitive exclusion and microbiota restoration | |
| Voriconazole clinical practice | Voriconazole clinical practice | Instituto de Investigación Hospital Universitario La Paz | marketed | Triazole antifungal | Fungal cytochrome P450 lanosterol 14α-demethylase (CYP51) | |
| anidulafungin and voriconazole | anidulafungin and voriconazole | Pfizer | marketed | Echinocandin and triazole antifungal combination | β-1,3-glucan synthase (anidulafungin); fungal CYP51/lanosterol 14α-demethylase (voriconazole) | |
| Nizoral® | Nizoral® | Ache Laboratorios Farmaceuticos S.A. | marketed | Imidazole antifungal | Lanosterol 14α-demethylase (CYP51) | |
| Terconazole Vaginal Suppository | Terconazole Vaginal Suppository | Hatem AbuHashim | marketed | Azole antifungal | Lanosterol 14α-demethylase (CYP51) | |
| Loceryl NL 12 weeks | Loceryl NL 12 weeks | Galderma R&D | marketed | Allylamine antifungal | Lanosterol 14α-demethylase (CYP51) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Azole antifungal class)
- Pfizer · 3 drugs in this class
- Elion Therapeutics, Inc. · 1 drug in this class
- Hadassah Medical Organization · 1 drug in this class
- Hatem AbuHashim · 1 drug in this class
- Janssen Pharmaceutical K.K. · 1 drug in this class
- Jiangsu Aosaikang Pharmaceutical Co., Ltd. · 1 drug in this class
- Military Hospital of Tunis · 1 drug in this class
- Mycovia Pharmaceuticals Inc. · 1 drug in this class
- Nuvation Bio Inc. · 1 drug in this class
- Purdue Pharma LP · 1 drug in this class
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Cite this brief
Drug Landscape (2026). voriconazole (VFEND®) — Competitive Intelligence Brief. https://druglandscape.com/ci/voriconazole-vfend. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing