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Vonoprazan-Amoxicillin with Berberine — Competitive Intelligence Brief
marketed
H. pylori eradication therapy (combination: proton pump inhibitor alternative + beta-lactam antibiotic + herbal antimicrobial)
H+/K+-ATPase (vonoprazan); bacterial cell wall (amoxicillin); multiple H. pylori targets (berberine)
Gastroenterology / Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Vonoprazan-Amoxicillin with Berberine (Vonoprazan-Amoxicillin with Berberine) — Nanjing First Hospital, Nanjing Medical University. This combination uses vonoprazan to suppress gastric acid, amoxicillin to kill H. pylori bacteria, and berberine as an adjunctive antimicrobial and anti-inflammatory agent for H. pylori eradication.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vonoprazan-Amoxicillin with Berberine TARGET | Vonoprazan-Amoxicillin with Berberine | Nanjing First Hospital, Nanjing Medical University | marketed | H. pylori eradication therapy (combination: proton pump inhibitor alternative + beta-lactam antibiotic + herbal antimicrobial) | H+/K+-ATPase (vonoprazan); bacterial cell wall (amoxicillin); multiple H. pylori targets (berberine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (H. pylori eradication therapy (combination: proton pump inhibitor alternative + beta-lactam antibiotic + herbal antimicrobial) class)
- Nanjing First Hospital, Nanjing Medical University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vonoprazan-Amoxicillin with Berberine — Competitive Intelligence Brief. https://druglandscape.com/ci/vonoprazan-amoxicillin-with-berberine. Accessed 2026-05-17.
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